Saturday's 26-21 reverse at the hands of South Africa's first team is the only blot on the Lions' copy book so far and the wider squad will be keen to get as much momentum as possible into the Lions camp ahead of next weekend's second international in Pretoria.
Tuesday's encounter with the most promising players in the Republic is the last mid-week fixture of the 10-match tour and could therefore be the final time some members of the touring party feature in Lions colours.
It also represents a chance for players on the fringes of selection to press their claims for a place in the matchday 22 for Saturday's must-win second Test at the home of Super 14 Champions the Bulls.
The Lions certainly won't be expecting an easy ride at the venue of their first Test win over the Boks 12 years ago as the Emerging Springboks are made up those players thought good enough to play for their country in the near future but who have not yet won a Test cap.
As a result, the squad features an array of prodigious talent, all with a point to prove.
The likes of scrum-half Jano Vermaak and full back Zane Kirchner were considered unfortunate to miss out on selection for the senior Springbok side, while utility back Earl Rose and centre Morgan Newman are both part of the wider South African squad.
Players such as back row Jean Deysel, prop Wian du Preez and hooker Tiaan Liebenberg have all played against the Lions for their provincial sides earlier on the tour, with the Lions coming out on top on each occasion.
No doubt they and players such as second row Steven Sykes, wing Luzuko Vulindlu and skipper Jacques Botes will be desperate gain some sort of revenge at Newlands.
The Emerging Boks are coached by South Africa's assistant coach Dick Muir who saw the Lions close up at the ABSA Stadium on Saturday afternoon. He will know all too well the importance of confidence and momentum going into next weekend's middle rubber and if his side can take the Lions' scalp in the build up, Muir will believe it could be crucial blow to the tourists' chances of overall Test success.
If we the British and Irish public are not fully acquainted with some of the less familiar figures in the Emerging Springbok squad, then Springbok head coach Peter de Villiers feels Tuesday's game could result in the creation of a number of household names. The former Baby Boks coach has already shown his faith in the next generation of South African stars, suggesting that the Lions will be in for a tough time come Tuesday evening.
"It's a very talented side and we look forward to them making the step up," said de Villiers.
"It shows the depth of rugby talent in this country and I am sure they will do us proud.
"We expect that some of these names will be there in 2011 (for the World Cup), so I believe they will definitely give the Lions their money's worth."