The Lions travel to South Africa in just nine months time but, before that, the Springboks will take on Wales, England and Scotland as they tour the UK.
Wales, who lost twice to Peter de Villiers' men on their summer tour but are the current Grand Slam and Six Nations Champions, face all three Southern Hemisphere giants, along with Canada, this November.
"South Africa is the best chance of a win," Evans said on BBC Wales' Scrum V.
"Australia are probably the most innovative and New Zealand are going to be a handful."
Evans, who won 72 caps for his country between 1987 and 1998, believes an uncertainty over style and a large degree of fatigue will prevent the Boks from being at their best when they run out at the Millennium Stadium on November 8.
"South Africa are still unsure what sort of game they want to play," said Evans.
"Also, a lot of their players are looking tired. Butch James has played two years of solid rugby."
Wales' autumn internationals
November 8 - South Africa
November 14 - Canada
November 22 - New Zealand
November 29 - Australia