Winger Akona Ndungane, full-back Jon-Paul Pietersen, flanker Pierre Spies and hooker Mahlatse 'Chiliboy' Ralepelle have all been drafted in as White looks to inject some young blood into his squad.
The 28 players will meet up in Johannesburg on Monday July 3 before leaving for Australia on July 6. Injured winger Bryan Habana (rib) will join the squad for assessment.
The Springboks' opening Tri-Nations clash sees them face Australia in Brisbane on July 15.
South Africa squad:
Forwards: Eddie Andrews, Bakkies Botha, Os Du Randt, Victor Matfield, Chiliboy Ralepelle, Lawrence Sephaka, John Smit (captain), Juan Smith, Pierre Spies, Albert Van Den Berg, CJ Van Der Linde, Joe Van Niekerk, Jacques Cronje, Danie Coetzee, Solomzi Tyibilika, Danie Rossouw.
Backs: Jean De Villiers, Jaco Van Der Westhuyzen, Jaque Fourie, Enrico Januarie, Percy Montgomery, Akona Ndungane, Wynand Olivier, Breyton Paulse, JP Pietersen, AndrÃ© Pretorius, Brent Russell, Fourie Du Preez.