Former Blues centre Tipoki's inclusion has sparked a re-shuffle of the team's backline for the visit of Queensland Reds.
Tipoki, a replacement in the defeat to his former side at Eden Park last week, slips into inside centre.
Casey Laulala moves into the midfield, with Caleb Ralph moving out to the wing and Scott Hamilton to full back in place of Brent Ward.
Crusaders: Scott Hamilton, Rico Gear, Casey Laulala, Rua Tipoki, Caleb Ralph, Stephen Brett, Andrew Ellis, Ben Franks, Corey Flynn (captain), Campbell Johnstone, Ross Filipo, Kevin O'Neill, Kieran Read, Johnny Leo'o, Mose Tuiali'I.
Reserves: Ti'i Paulo, Wyatt Crockett, Michael Paterson, Jake Paringatai, Kevin Senio, Tusi Pisi, Brent Ward.