Fly-half Gerald Merceron has been replaced by Francois Gelez after missing two penalties and a conversion in the 25-17 defeat to England at Twickenham.
And coach Bernard Laporte has included Stade Francais prop Sylvain Marconnet at the expense of Christian Califano.
Scotland themselves suffered defeat in their RBS 6 Nations opener against Ireland at Murrayfield.
But the Sale Sharks scrum-half is adamant that the Scottish team must maintain their focus on Sunday's opponents rather than the changes in the opposition ranks.
Redpath said: "I'm not interested really. I'm just making sure we get ourselves performing better than we did last week.
"Whoever they choose they're going to be a very strong side.
"The players they're bringing in are quality and the players that are leaving are quality but if we don't get our part right it doesn't matter who you're playing against."