For at least seven of those players named in their country's starting XV for this weekend's games, the Lions tour to South Africa would have seemed an incredibly long way off just weeks ago. Now, though, Keith Earls, Leigh Halfpenny, Andy Powell, Delon Armitage, Ugo Monye, Riki Flutey and Nick Kennedy are all one step closer to the ultimate honour.
Irishman Earls, Welsh duo Halfpenny and Powell, and England quartet Armitage, Monye, Flutey and Kennedy will all make their international bows on Saturday afternoon.
Munster full back Keith Earls has been rewarded for a fine start to the season with a first appearance in Ireland colours against Canada at Thomond Park, while Leigh Halfpenny and Andy Powell will both make their Wales debuts in the clash with South Africa in Cardiff a few hours earlier.
Former Lions captain Martin Johnson has named Armitage, Monye, Flutey and Kennedy at full back, wing, inside centre and lock respectively for the match against the Pacific Islanders at Twickenham on Saturday as England warm up for successive fixtures against Australia, South Africa and New Zealand.
Scotland are the only one of the four countries that contribute to a Lions squad not to include an uncapped player in their matchday 22, but their mouth-watering encounter with the All Blacks will see Glasgow wing Thom Evans make just his second appearance at senior international level.
England vs Pacific Islanders, Saturday, 2.30pm:
D Armitage (London Irish); Sackey (Wasps), Noon (Newcastle), Flutey (Wasps), Monye (Harlequins); Cipriani (Wasps), Care (Harlequins); Sheridan (Sale), Mears (Bath), Stevens (Bath), Borthwick (Saracens, captain), Kennedy (London Irish), Croft (Leicester), Rees (Wasps), Easter (Harlequins)
Replacements: Hartley (Northampton), Vickery (Wasps), Palmer (Wasps), Haskell (Wasps), Lipman (Bath), Ellis (Leicester), Flood (Leicester)
Wales vs South Africa, Saturday, 2.30pm:
Lee Byrne (Ospreys); Leigh Halfpenny (Cardiff Blues), Jamie Roberts (Cardiff Blues), Gavin Henson (Ospreys), Shane Williams (Ospreys); Stephen Jones (Scarlets), Gareth Cooper (Gloucester); Gethin Jenkins (Cardiff Blues), Matthew Rees (Scarlets), Adam Jones (Ospreys), Alun Wyn Jones (Ospreys), Ian Evans (Ospreys), Ryan Jones (Ospreys, capt), Martyn Williams (Cardiff Blues), Andy Powell (Cardiff Blues)
Replacements: Richard Hibbard (Ospreys), Duncan Jones (Ospreys), Ian Gough (Ospreys), Dafydd Jones (Scarlets), Dwayne Peel (Sale Sharks), James Hook (Ospreys), Tom Shanklin (Cardiff Blues)
Ireland vs Canada, Saturday, 5.15pm:
Earls; Bowe, O'Driscoll, capt, Fitzgerald, Kearney; O'Gara, Reddan; Horan, Flannery, Buckley, O'Callaghan, O'Connell, Ferris, Jennings, Heaslip
Replacements (from): R Best, Hayes, Caldwell, Quinlan, D Wallace, P Wallace, Stringer, Horgan
Scotland vs New Zealand, Saturday, 5.15pm:
Paterson (Edinburgh); Evans (Glasgow Warriors), Cairns (Edinburgh), De Luca (Edinburgh), S Lamont (Northampton); Godman (Edinburgh), Blair (Edinburgh, capt); Jacobsen (Edinburgh), Ford (Edinburgh), E Murray (Northampton), Hines (Perpignan), Hamilton (Edinburgh), White (Sale), Taylor (Stade Francais), Barclay (Glasgow Warriors)
Replacements: Hall (Glasgow Warriors), Dickinson (Gloucester), Mustchin (Edinburgh), Gray (Northampton), Lawson (Gloucester) or McMillan (Glasgow Warriors), Parks (Glasgow Warriors), Southwell (Edinburgh)