Jones, who was part of the Grand Slam winning side earlier this year, picked up a knee injury during the Scarlets' final match at Stradey Park last weekend.
"Mark Jones' knee is still puffy at this point, he's still limping around," said head coach Warren Gatland during Wales training this week.
"We'll wait and see when he comes in on Monday, but I'd say he's the one who's very doubtful at the moment."
Bath youngster Abendanon was only recently called into Martin Johnson's Elite Player Squad but an injury to his big toe on his left foot has seen him released back to his club.
The 22-year-old is expected to be out of action for between two to four weeks.
His removal from the England camp follows Johnson's decision to send eight players, Olly Barkley, George Chuter, Jordan Crane, Shane Geraghty, Dan Hipkiss, Josh Lewsey, Tim Payne and Peter Richards, back to their clubs on Tuesday.
Despite the absence of Abendanon and Lewsey, Johnson has declined to call another full back into his squad for next Saturday's game against the Pacific Islanders.
With Matthew Tait struggling with a hamstring injury, Delon Armiitage of London Irish is the only fully fit full back in Johnson's squad.