Frenchman Joel Jutge will take charge of England's opening autumn Test against New Zealand at Twickenham on November 5.
New Zealander Kelvin Deaker has been handed England's November 11 clash with Argentina, while the two Tests against South Africa on November 18 and 25 will be in the respective hands of Steve Walsh and Alain Rolland.
Walsh, meanwhile, will also be in control of Wales' first autumn game against Australia at the Millennium Stadium.
Autumn Test referee appointments
November 4, Wales v Australia (Steve Walsh); November 5, England v New Zealand (Joel Jutge); November 11, Ireland v South Africa (Paul Honiss), England v Argentina (Kelvin Deaker), Wales v Pacific Islands (Wayne Barnes), Scotland v Romania (Matt Goddard).
November 17, Wales v Canada (Tony Spreadbury), November 18, England v South Africa (Steve Walsh), Scotland v Pacific Islands (Bryce Lawrence); November 19, Ireland v Australia (Marius Jonker).
November 25, England v South Africa (Alain Rolland), Scotland v Australia (Donal Courtney), Wales v New Zealand (Dave Pearson); November 26, Ireland v Pacific Islands (Christophe Berdos).