Jackson missed the opening two rounds of the 6 Nations with a hamstring injury but could now win a promotion to the matchday 22 this weekend.
The 23-year-old has featured in both of Glasgow's last two RaboDirect PRO12 games, coming through the win over the Scarlets and the draw with Connacht unscathed.
Jackson will now look to challenge Edinburgh's Greig Laidlaw for the Scotland No10 shirt after the former scrum-half started his first Test in Cardiff just over a week ago.
Jackson was his country's first-choice playmaker for much of last season and his return gives head coach Andy Robinson some added experience in that role.
Veteran Dan Parks was handed the fly-half berth against England after Robinson managed to persuade him to postpone his retirement but the 32-year-old has since called time on his Test career.
With Jackson still struggling, Robinson was left with two inexperienced 10s to choose from in Laidlaw and Glasgow's Duncan Weir and, although Laidlaw showed plenty of promise against the Welsh, it would be a major surprise if Jackson didn't play some part in the action in Round 3.
Elsewhere in the squad, Scotland have injury concerns over wing Max Evans and second row Jim Hamilton, No8 Richie Vernon and hooker Scott Lawson.
Evans is continuing his rehabilitation after picking up an ankle knock at the Millennium Stadium, while Gloucester's Hamilton has a throat infection.
Vernon and Lawson - who looks set to play his club rugby in Scotland next season - have ankle and dead leg worries respectively, but prop Ed Kalman is back in training following a neck injury.