I think England will win by a reasonable margin but they have made six changes and Italy have improved over the last couple of years. England have got to put them away and they need to do it in some style as Italy won't just roll over.
The changes are interesting as it gives Clive Woodward a chance to look at some other players, which he needs to do ahead of the World Cup. You need a full squad for that.
I don't have a problem with Jonny Wilkinson being made captain for the first time as he seems to take everything in his stride and I can't see it causing any difficulties for him. He has captained Newcastle and he has got some great leaders around him on the pitch if he needs a hand but it's much easier being captain of a team who win regularly.
Mike Tindall has come in for Charlie Hodgson, and I think the experiment to play Charlie out of position for the last two games has not worked. It has given him some experience but it is difficult to play well out of position at international level.
Mike does a straightforward job, he carries the ball well which is important with Ben Cohen missing, and he makes good ground.
Danny Grewcock comes in for Martin Johnson and we all know he is an international-class player while flanker Joe Worsley has been playing well for Wasps and it is up to him to take his chance - as it is for all the players in what is a very important match for England.