Unsurprisingly then, Kirwan has named an unchanged side to face the Irish with the only switch coming on the bench where Martin Leandro Castrogiovanni replaces Salvatore Perugini who pulled a thigh muscle after being on the pitch for just 30 seconds against the Welsh.
However, Ireland's thrilling 36-6 victory over Scotland at Murrayfield confirmed the feeling of many that they are potential title challengers this year.
David Humphreys, who posted 26 points, retains his place at stand-off with Ronan O'Gara still injured.
The only new face in the starting line-up is Geordan Murphy whose spectacular try as a replacement against the Scots gives him the nod over Shane Horgan.
However, if full-back Girvan Dempsey does not pass a fitness test then Murphy may take the number 15 jersey with John Kelly filling in on the wing.
Starting on the bench is centre Rob Henderson who scored a career-highlight hat-trick of tries when Ireland visited the Stadio Flaminio two years ago.
Ireland's star centre Brian O'Driscoll admitted he was impressed with Italy's development.
He said: "They seem to be much better drilled defensively, a lot stronger and they seem to know what they want out of their defence."