Andrew revealed the England star's recovery is progressing well but is adamant he should not be rushed into an international comeback.
Andrew told The Times: "The recovery is going very well but the key will be how he is reintroduced.
"That can only be through a club game, probably off the bench.
"It would be irresponsible to put him straight into a Test match.
"For the Harlequins game he might be close, but it is touch and go.
"We can't afford to get it wrong with a knee injury."
The news means that the only chance Wilkinson will have to prove his fitness for the Lions tour will be for his club.