Irish tight head prop Paul Wallace gave the Free State legend a torrid time in the Test series 12 years ago and the now the retired du Randt has warned the Springboks not to get ambushed a second time.
"We must take on the Lions in the forwards. They are coming with the same mentality, same coach and same tactics that they had in 1997, with big, heavy guys," he told the Cape Times.
"They are used to scrumming and making the game slower. So we must match them physically and try to get the ball to the wings, but we mustn't only play champagne rugby.
"During the first 30 to 40 minutes, it will be very important to mix it up, and then we must win in the last 30 minutes. We must take the game to them. I also think we must kick just a bit more tactically, to put extra pressure on them."
De Villiers only included one specialist tight head prop in his 23-man training squad to face a Namibian Invitational XV on 29 May, the skipper John Smit, and du Randt is worried there is not enough strength in depth in the front row to combat the experience and size in the Lions pack.