Newcastle forward Charvis is suffering from a foot problem and faces at least another fortnight on the sidelines, while Cardiff Blues skipper Williams has disc trouble in his neck.
Wales coach Mike Ruddock has drafted Neath-Swansea Ospreys forward Richie Pugh into the Six Nations squad as cover for vice-captain Charvis, with Cardiff's Robin Sowden-Taylor also called up to train.
Wales have not beaten in England in Cardiff since 1993, but the probable loss of Charvis, especially, has dented their victory hopes.







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